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The effector CD4 and CD8 T cells that Tregs inhibit from functioningduring either an autoimmune response or an anti-tumor response not only elaborate a plethoraof cytokines but also have the capability to kill target cells using the granulocytic system,which involves injecting perforins into their target.
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(L)EER achieved a 100% R0 resection ratewithout abortion of any procedure during the resective phase.6 R0 resection has beenproven to be the most important factor for pelvic tumor control and cure.7 Locoregionaltumor control of 90% and overall survival rates of 60% have been obtained in thetreatment of locally advanced and recurrent cancer, the majority of them being tumorsfixed to the pelvic side wall, which are usually not considered for surgical treatment at all.Late complications are listed in table 9-1.
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